The Laboratory System’s Strengthening Community of Practice (LabCoP) 6th Annual Meeting report presents key summaries, proposed actions and recommendations from the 2022 annual meeting. Held in Cape Town, South Africa from 11-13 October 2022, this hybrid in-person and virtual meeting brought together 19 country teams, funding agencies, ASLM collaborating partners and the LabCoP Management Team. At the meeting, relevant topics of importance were discussed, including systems to facilitate the return of test results, community testing and access to diagnostics, waste management (WM), and effective diagnostic strategies to control and prevent HIV, Coronavirus Disease 2019 (COVID-19), and tuberculosis. Please use the links below to download the meeting report, available in both English and French.