SARS-CoV-2 and COVID-19: The Most Important Research Questions
This paper highlights important research questions regarding SARS-CoV-2 which include origin, virus transmission, viral shedding, diagnosis, treatment, vaccine development and vira
Temporal Dynamics in Viral Shedding and Transmissibility of COVID-19
This study, by Xi He et al, published in Nature Medicine (15 April, 2020), reports that 44% of secondary COVID-19 cases were transmitted by people who had not yet developed symptom
Trial of Lopinavir–Ritonavir in Adults Hospitalised with Severe COVID-19
This study by Dr Bin Cao, et al, 2020, in the New England Journal of Medicine describes a trial of lopinavir–ritonavir in adults hospitalised with severe COVID-19 where no benefi
Systematic Review of the Efficacy and Safety of ARVs Against SARS, MERS, or COVID-19
This systematic review of the efficacy and safety of antiretroviral drugs against SARS, MERS, or COVID-19 (initial assessment) was conducted by Dr Nathan Ford, et al, 2020. Their c
Preparedness and Vulnerability of African Countries Against Importations of COVID-19
This modelling study by Marius Gilbert, et al, published in the Lancet, 2020, evaluates preparedness and vulnerability of African countries against importations of COVID-19. Their
Clinical Characteristics of COVID-19 in China
This article published in the New England Journal of Medicine by W. Guan, et al, 2020, describes the clinical characteristics of affected patients with COVID-19 in China. The findi
Aerosol and Surface Stability of HCoV-19 (SARS-CoV-2) compared to SARS-CoV-1
This paper published in the New England Journal of Medicine by Neeltje van Doremalen, et al, 2020, describes the stability of viable SARS-CoV-2 on surfaces and in aerosols in compa
2019-nCoV: Structure, Characteristics of Key Potential Therapy Target Determined
This article by Mark S. Lesney and published by MDedge, 2020, highlights the news that researchers have identified the structure of a spike protein that could turn out to be a pote
COVID-19 Treatment: A Review of Early and Emerging Options
This paper by Erin K. McCreary and Jason M. Pogue about COVID-19 treatment describes a review of early and emerging options. The authors summarize the current evidence as of 19 Mar
An Acute Respiratory Infection Runs Into The Most Common Non-communicable Epidemic
This paper by Chengzhi Yang & Zening Jin, 2020, indicated that individuals with underlying chronic cardiovascular diseases (CVDs) were both more susceptible to COVID-19 and mor