Xpert HIV-1 Viral Load is an in vitro reverse transcriptase polymerase chain reaction (RT PCR) assay for the detection and quantification of HIV-1 RNA in human plasma from HIV-1 infected individuals.

Manufacturer: Cepheid AB (Sunnyvale, CA, USA)

Instrument Compatibility: GeneXpert Dx, GeneXpert Infinity-48s and GeneXpert Infinity-80

Detects: HIV-1

Quality Standards: WHO PQ; CE marked 

WHO Reference Numbers: PQ Dx 0192-070-001, PQ Dx 0194-070-00, PQ Dx 0195-070-00

Listing Date: 20 July 2017

Three systematic reviews have been published (Nash et al 2018; Agutu et al 2019; Sacks et al 2019) synthesising data from 13 studies that have assessed the performance of the Xpert HIV-1 Viral Load assay as compared with current reference standards. Overall, Xpert HIV-1 Viral Load assay performed well with high sensitivity, high specificity, and limited bias.